Skip to content

Zollinger-ellison Syndrome

Zollinger-Ellison syndrome is a rare condition in which tumours called gastrinomas, usually found in the pancreas or the duodenum, release a hormone that pushes the stomach to make far too much acid. The excess acid causes ulcers that are severe and keep returning. Specialists diagnose and manage it.

Medicine used to treat Zollinger-ellison Syndrome

Pepcid

Famotidine

20 · 40mg

Pepcid contains famotidine to lower stomach acid in gastro-oesophageal reflux disease, peptic ulcer disease and Zollinger-Ellison syndrome. It comes as tablets in several strengths and pack sizes. You see the price per tablet for each option.

FromUS$0.27/ tabletView

Key points

  • Gastrinomas are the tumours behind the condition, and they most often sit in the pancreas or the duodenum.
  • The acid problem is continuous, so ulcers are severe and recur rather than settling after one episode.
  • Famotidine is one of the acid-lowering medicines used to control symptoms; assessment and removal of the tumour is a specialist decision.

What causes the excess acid

A gastrinoma releases a hormone that signals the stomach to secrete acid well beyond normal needs. Because the tumour keeps producing that signal, the stomach keeps responding, and ulcers form and reform. Confirming the diagnosis is a specialist task.

The ulcer pattern

Ulceration here is not a single event. It is severe and repeated, which is why persistent or returning ulcers are investigated further. The pattern of recurrence is part of what leads to specialist referral.

How it is treated

Acid-lowering medicines are used to control symptoms, and famotidine is one option; it is supplied as Pepcid tablets in 20 mg and 40 mg strengths, and the same ingredient is described on the famotidine page. The tumours themselves are assessed by a specialist team and removed where that is possible. Pharmacy partners in India ship orders to Malaysia in discreet packaging.

When to see a doctor

Severe ulcers, or ulcers that keep coming back after treatment, need medical assessment. Because the condition is uncommon and involves a tumour, care sits with specialists rather than being managed with acid suppression alone.

Further reading

Last updated