Lamotrigine is an antiepileptic medicine used for epilepsy and bipolar disorder. It is taken by mouth and acts on nerve signalling to control seizures and stabilise mood. It belongs to the phenyltriazine class.
Epilepsy, Bipolar Disorder
25 · 50 · 100 · 200mg
Lamotrigine tablets contain lamotrigine, an anticonvulsant for epilepsy and for preventing mood episodes in bipolar disorder. You can choose from several strengths and pack sizes. You see the price per tablet for each option.
Lamotrigine has two main uses: epilepsy and bipolar disorder. In epilepsy it is used for partial or generalised seizures. In bipolar disorder it helps lengthen the time between mood episodes and supports mood stabilisation. Both uses relate to altered nerve signalling.
Lamotrigine stabilises neuronal membranes by inhibiting voltage-gated sodium channels. This limits the release of excitatory neurotransmitters such as glutamate. The effect supports control of seizure thresholds and mood stabilisation. This action underpins both its antiepileptic and mood-stabilising effects. Onset is 1–3 hours, and the duration is 24–36 hours.
Lamotrigine comes as a tablet and as a dispersible tablet. The Lamotrigine tablet from MayChemist is available in 25 mg, 50 mg, 100 mg and 200 mg strengths. The active ingredient is lamotrigine. The dispersible tablet is an alternative to the standard tablet. Pharmacy partners in India ship orders to Malaysia in discreet packaging.
Do not take lamotrigine if you have had a hypersensitivity reaction to it. Serious skin rashes, including Stevens-Johnson syndrome and toxic epidermal necrolysis, require immediate medical attention. Haemophagocytic lymphohistiocytosis also requires immediate medical attention. Watch for signs of hypersensitivity, and avoid stopping lamotrigine abruptly without medical advice. Any history of skin rash needs particular attention.
Common side effects include headache, dizziness, nausea and somnolence. Diplopia, blurred vision and ataxia are moderate effects to report. Report persistent or troublesome effects to a healthcare professional. Lamotrigine interacts with valproate, carbamazepine, phenytoin and hormonal contraceptives. Use in pregnancy is with caution because risks to the foetus are being evaluated. Small amounts pass into breast milk, so monitoring is recommended.
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